Nanoemulsion composite microgels for orthogonal encapsulation and release.

Polymer hydrogels and microgels have been widely exploited for the controlled storage, delivery and detection of active compounds, including small molecules and biologics. [ 1 , 2 ] However, due to their intrinsically hydrated microenvironment, the development of hydrogels for encapsulation and/or release of poorly water-soluble cargos remains a persistent challenge. [ 3 ] As such, the development of novel hydrogels with well-controlled hydrophobic compartments remains important to a number of delivery applications including pharmaceuticals, [ 3 , 4 ] cosmetics, [ 5 ]